Creative Biolabs-Immuno-oncology

Anti-GUCY2C (clone C2E7J) SynExpress E1-mKa-cJ-K Modified CD8+ T cells (CAT#: ITS-1224-CR444)

DatasheetDatasheet
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target GUCY2C (clone C2E7J). We employs the Retrovirus (EF1α-mKate-c-Jun-KpnI) vector components and the SynExpress system of the Exons Knockout/Negative feedback for a robust and sustained response against cancers.
Host
Camel
Target
GUCY2C
Clone
C2E7J
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mKate
Promoter
EF1α
Effector Gene
c-Jun
Insertion Sites
KpnI
Gene Modification
Knockout
Modification Domain
Exons
Carrier Type
Retrovirus
Transformation Accuracy
0.98
Cell Culture
Adherent Culture
Case Studies
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