Anti-HER2 (clone 4B34D) SynExpress pB-BF-I17-X CD8+ T Cells

CAT#: ITS-1124-CR125
Clone: 4B34D
Host: Human
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: pBAD-BFP-IL-17-XbaI
Carrier Type: HBV
Description
This product utilizes CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target HER2 ( clone 4B34D). We employs the HBV (pBAD-BFP-IL-17-XbaI) vector components and the SynExpress system of the miRNA Knock-in/Positive feedback for a robust and sustained response against cancers.
Host
Human
Target
HER2
Clone
4B34D
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
BFP
Promoter
pBAD
Effector Gene
IL-17
Insertion Sites
XbaI
Gene Modification
Knock-in
Modification Domain
miRNA
Carrier Type
HBV
Transformation Accuracy
0.88
Cell Culture
Aseptic Culture
Target
HER2
Alternative Names
ERBB2; CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1; erb-b2 receptor tyrosine kinase 2
Gene ID
P27930(Human)
UniProt ID
2064(Human); 13866(Mouse)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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