Anti-ICOS (clone 4I2E2E.2E) SynExpress T7-R-I4-H Modified CD8+ T cells

CAT#: ITS-1224-CR233
Clone: 4I2E2E.2E
Host: Mouse
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: T7-RFP-IL-4-HindIII
Carrier Type: pBR322
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target ICOS (clone 4I2E2E.2E). We employs the pBR322 (T7-RFP-IL-4-HindIII) vector components and the SynExpress system of the Coding regions Deletion/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
ICOS
Clone
4I2E2E.2E
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
RFP
Promoter
T7
Effector Gene
IL-4
Insertion Sites
HindIII
Gene Modification
Deletion
Modification Domain
Coding regions
Carrier Type
pBR322
Transformation Accuracy
0.87
Cell Culture
Suspension Culture
Target
ICOS
Alternative Names
ICOS; AILIM; CD278; CVID1; inducible T-cell co-stimulator; inducible T-cell costimulator; inducible T cell costimulator
Gene ID
Q5XXA6(Human)
UniProt ID
29851(Human); 54167(Mouse); 64545(Rat)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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