Creative Biolabs-Immuno-oncology

Anti-ICOS (clone Z0Z4I) SynExpress SV-Cy5-I4-E Synthetic CD4+ T cells (CAT#: ITS-1224-CR227)

DatasheetDatasheet
Description
This product utilizes Synthetic CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target ICOS (clone Z0Z4I). We employs the AAV (SV40-Cy5-IL-4-EcoRI) vector components and the SynExpress system of the lncRNA Base Editing/Positive feedback for a robust and sustained response against cancers.
Host
humanized
Target
ICOS
Clone
Z0Z4I
Species Reactivity
Human
Cell Source
Synthetic CD4+ T cells
Sensor Gene
Cy5
Promoter
SV40
Effector Gene
IL-4
Insertion Sites
EcoRI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
AAV
Transformation Accuracy
0.95
Cell Culture
Suspension Culture
Case Studies
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