Anti-ICOS (clone Z0Z5L) SynExpress T7-G-cJ-K Modified CD8+ T cells

CAT#: ITS-1224-CR228
Clone: Z0Z5L
Host: humanized
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: T7-GFP-c-Jun-KpnI
Carrier Type: Adenovirus
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target ICOS (clone Z0Z5L). We employs the Adenovirus (T7-GFP-c-Jun-KpnI) vector components and the SynExpress system of the miRNA Knock-in/Negative feedback for a robust and sustained response against cancers.
Host
humanized
Target
ICOS
Clone
Z0Z5L
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
GFP
Promoter
T7
Effector Gene
c-Jun
Insertion Sites
KpnI
Gene Modification
Knock-in
Modification Domain
miRNA
Carrier Type
Adenovirus
Transformation Accuracy
0.89
Cell Culture
Plate Culture
Target
ICOS
Alternative Names
ICOS; AILIM; CD278; CVID1; inducible T-cell co-stimulator; inducible T-cell costimulator; inducible T cell costimulator
Gene ID
Q5XXA6(Human)
UniProt ID
29851(Human); 54167(Mouse); 64545(Rat)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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