Anti-ICOS (clone Z0Z7J) SynExpress E1-G-β-Sm γδ T cells

CAT#: ITS-1224-CR230
Clone: Z0Z7J
Host: humanized
Cell Source: γδ T cells
Species Reactivity: Human
Connector Fragments: EF1α-GFP-β-catenin-SmaI
Carrier Type: pCDNA
Description
This product utilizes γδ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target ICOS (clone Z0Z7J). We employs the pCDNA (EF1α-GFP-β-catenin-SmaI) vector components and the SynExpress system of the Single base pair Knockout/Positive feedback for a robust and sustained response against cancers.
Host
humanized
Target
ICOS
Clone
Z0Z7J
Species Reactivity
Human
Cell Source
γδ T cells
Sensor Gene
GFP
Promoter
EF1α
Effector Gene
β-catenin
Insertion Sites
SmaI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
pCDNA
Transformation Accuracy
0.91
Cell Culture
3D Culture
Target
ICOS
Alternative Names
ICOS; AILIM; CD278; CVID1; inducible T-cell co-stimulator; inducible T-cell costimulator; inducible T cell costimulator
Gene ID
Q5XXA6(Human)
UniProt ID
29851(Human); 54167(Mouse); 64545(Rat)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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