Anti-ICOS (clone Z0Z8P) SynExpress C-mSc-TF2-E Regulatory B cells

CAT#: ITS-1224-CR231
Clone: Z0Z8P
Host: humanized
Cell Source: Regulatory B cells
Species Reactivity: Human
Connector Fragments: CMV-mScarlet-TFIIB-EcoRI
Carrier Type: Adenovirus
Description
This product utilizes Regulatory B cells that have been engineered with our proprietary GeneCircuit technology to specifically target ICOS (clone Z0Z8P). We employs the Adenovirus (CMV-mScarlet-TFIIB-EcoRI) vector components and the SynExpress system of the DNA methylation sites Knock-in/Balancing feedback for a robust and sustained response against cancers.
Host
humanized
Target
ICOS
Clone
Z0Z8P
Species Reactivity
Human
Cell Source
Regulatory B cells
Sensor Gene
mScarlet
Promoter
CMV
Effector Gene
TFIIB
Insertion Sites
EcoRI
Gene Modification
Knock-in
Modification Domain
DNA methylation sites
Carrier Type
Adenovirus
Transformation Accuracy
0.95
Cell Culture
Aseptic Culture
Target
ICOS
Alternative Names
ICOS; AILIM; CD278; CVID1; inducible T-cell co-stimulator; inducible T-cell costimulator; inducible T cell costimulator
Gene ID
Q5XXA6(Human)
UniProt ID
29851(Human); 54167(Mouse); 64545(Rat)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
Online Inquiry