Anti-ICOSL (clone 1GD7J) SynExpress E1-G-I10-Sm γδ T cells

CAT#: ITS-1224-CR240
Clone: 1GD7J
Host: humanized
Cell Source: γδ T cells
Species Reactivity: Human
Connector Fragments: EF1α-GFP-IL-10-SmaI
Carrier Type: Adenovirus
Description
This product utilizes γδ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target ICOSL (clone 1GD7J). We employs the Adenovirus (EF1α-GFP-IL-10-SmaI) vector components and the SynExpress system of the DNA methylation sites Knock-in/Positive feedback for a robust and sustained response against cancers.
Host
humanized
Target
ICOSL
Clone
1GD7J
Species Reactivity
Human
Cell Source
γδ T cells
Sensor Gene
GFP
Promoter
EF1α
Effector Gene
IL-10
Insertion Sites
SmaI
Gene Modification
Knock-in
Modification Domain
DNA methylation sites
Carrier Type
Adenovirus
Transformation Accuracy
0.86
Cell Culture
Adherent Culture
Target
ICOSL
Alternative Names
ICOSLG; B7-H2; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS; inducible T-cell co-stimulator ligand; inducible T-cell costimulator ligand; inducible T cell costimulator ligand; B7h
Gene ID
Q62386(Mouse)
UniProt ID
23308(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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