Anti-ICOSLG (clone 4I1GH) SynExpress T7-R-β-E Synthetic CD4+ T cells

CAT#: ITS-1224-CR245
Clone: 4I1GH
Host: Human
Cell Source: Synthetic CD4+ T cells
Species Reactivity: Human
Connector Fragments: T7-RFP-β-catenin-EcoRI
Carrier Type: AAV
Description
This product utilizes Synthetic CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target ICOSLG (clone 4I1GH). We employs the AAV (T7-RFP-β-catenin-EcoRI) vector components and the SynExpress system of the lncRNA Base Editing/Adaptive feedback for a robust and sustained response against cancers.
Host
Human
Target
ICOSLG
Clone
4I1GH
Species Reactivity
Human
Cell Source
Synthetic CD4+ T cells
Sensor Gene
RFP
Promoter
T7
Effector Gene
β-catenin
Insertion Sites
EcoRI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
AAV
Transformation Accuracy
0.87
Cell Culture
Suspension Culture
Target
ICOSLG
Alternative Names
ICOSLG; B7-H2; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS; inducible T-cell co-stimulator ligand; inducible T-cell costimulator ligand; inducible T cell costimulator ligand; B7h
Gene ID
Q62386(Mouse)
UniProt ID
23308(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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