Creative Biolabs-Immuno-oncology

Anti-ITGA4 (clone C3RD2) SynExpress p15-Cy3-β-Sm γδ T cells (CAT#: ITS-1224-CR140)

DatasheetDatasheet
Description
This product utilizes γδ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target ITGA4 (clone C3RD2). We employs the AAV (p15A-Cy3-β-catenin-SmaI) vector components and the SynExpress system of the Single base pair Knockout/Negative feedback for a robust and sustained response against cancers.
Host
Humanized
Target
ITGA4
Clone
C3RD2
Species Reactivity
Human
Cell Source
γδ T cells
Sensor Gene
Cy3
Promoter
p15A
Effector Gene
β-catenin
Insertion Sites
SmaI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.94
Cell Culture
3D Culture
Case Studies
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