Creative Biolabs-Immuno-oncology

Anti-KIT (clone Hum4I) SynExpress E1-mCh-I17-B Synthetic CD4+ T cells (CAT#: ITS-1224-CR174)

DatasheetDatasheet
Description
This product utilizes Synthetic CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target KIT (clone Hum4I). We employs the pUC (EF1α-mCherry-IL-17-BamHI) vector components and the SynExpress system of the miRNA Prime Editing/Delayed feedback for a robust and sustained response against cancers.
Host
Human
Target
KIT
Clone
Hum4I
Species Reactivity
Human; Canine; Monkey
Cell Source
Synthetic CD4+ T cells
Sensor Gene
mCherry
Promoter
EF1α
Effector Gene
IL-17
Insertion Sites
BamHI
Gene Modification
Prime Editing
Modification Domain
miRNA
Carrier Type
pUC
Transformation Accuracy
0.95
Cell Culture
Plate Culture
Case Studies
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