Creative Biolabs-Immuno-oncology

Anti-LAG3 (clone 8PF6Z) SynExpress pB-BF-β-Sm Modified CD8+ T cells (CAT#: ITS-1224-CR1982)

DatasheetDatasheet
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target LAG3 (clone 8PF6Z). We employs the Lentivirus (pBAD-BFP-β-catenin-SmaI) vector components and the SynExpress system of the Multiple base pair Knockout/Positive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
LAG3
Clone
8PF6Z
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
BFP
Promoter
pBAD
Effector Gene
β-catenin
Insertion Sites
SmaI
Gene Modification
Knockout
Modification Domain
Multiple base pair
Carrier Type
Lentivirus
Transformation Accuracy
0.94
Cell Culture
Adherent Culture
Case Studies
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