Anti-LAG3 (clone 8PF6Z) SynExpress pB-BF-β-Sm Modified CD8+ T cells

CAT#: ITS-1224-CR1982
Clone: 8PF6Z
Host: Mouse
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: pBAD-BFP-β-catenin-SmaI
Carrier Type: Lentivirus
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target LAG3 (clone 8PF6Z). We employs the Lentivirus (pBAD-BFP-β-catenin-SmaI) vector components and the SynExpress system of the Multiple base pair Knockout/Positive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
LAG3
Clone
8PF6Z
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
BFP
Promoter
pBAD
Effector Gene
β-catenin
Insertion Sites
SmaI
Gene Modification
Knockout
Modification Domain
Multiple base pair
Carrier Type
Lentivirus
Transformation Accuracy
0.94
Cell Culture
Adherent Culture
Target
LAG3
Alternative Names
LAG3; CD223; lymphocyte activating 3
Gene ID
P18627(Human)
UniProt ID
3902(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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