This program aims to develop anti-MSLN therapeutic fusion protein for immuno-oncology.
Rationale when developing the program:
Given the above findings, we believe the novel fusion protein targeting MSLN will be a promising field for next-generation cancer therapy.
Although its biological function is not fully understood, the cancer-specific expression of MSLN makes it a potential therapeutic target to be researched in tumor studies. Currently, more research is still needed to verify its role in tumor metastasis.
Some highlighted data that have been verified:
Here is a schematic model showing the scFvMTBHsp70 fusion protein binding to MSLN in tumor cells.
(Yuan, 2014)
Creative Biolabs has extensive knowledge of end-to-end program development. For each program, we are committed to delivering the final complete program to our clients within 1.5 years before entering the IND stage.
Creative Biolabs is looking for potential partners (include but not limit to major pharma or biotech firms) to develop MSLN therapeutic fusion protein program. Our scientists are dedicated to bringing together years of valuable experience to our partner and achieve a meaningful partnership together. For any partners interested in our Next-IO™ programs, Creative Biolabs welcomes collaboration.
Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from the discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate for our programs.
With our quality control protocol and knowledge of global regulatory requirements, we can help our partners advance their programs with more chance to succeed. Look forward to cooperating with you in the near future.
For Research Use Only | Not For Clinical Use