Creative Biolabs-Immuno-oncology

Anti-MUC16 (clone 2E4IB3) SynExpress C-R-I10-X Regulatory B cells (CAT#: ITS-1224-CR1270)

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Description
This product utilizes Regulatory B cells that have been engineered with our proprietary GeneCircuit technology to specifically target MUC16 (clone 2E4IB3). We employs the AAV (CMV-RFP-IL-10-XbaI) vector components and the SynExpress system of the Single base pair Knockout/Positive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
MUC16
Clone
2E4IB3
Species Reactivity
Human
Cell Source
Regulatory B cells
Sensor Gene
RFP
Promoter
CMV
Effector Gene
IL-10
Insertion Sites
XbaI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.99
Cell Culture
Suspension Culture
Case Studies
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