Creative Biolabs-Immuno-oncology

Anti-MUC16 (clone 4I2E0Z9Q) SynExpress pU-mCh-cF-Sp Regulatory B cells (CAT#: ITS-1224-CR1258)

DatasheetDatasheet
Description
This product utilizes Regulatory B cells that have been engineered with our proprietary GeneCircuit technology to specifically target MUC16 (clone 4I2E0Z9Q). We employs the AAV (pUC-mCherry-c-Fos-SpeI) vector components and the SynExpress system of the lncRNA Base Editing/Balancing feedback for a robust and sustained response against cancers.
Host
Mouse
Target
MUC16
Clone
4I2E0Z9Q
Species Reactivity
Human
Cell Source
Regulatory B cells
Sensor Gene
mCherry
Promoter
pUC
Effector Gene
c-Fos
Insertion Sites
SpeI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
AAV
Transformation Accuracy
0.95
Cell Culture
Suspension Culture
Case Studies
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