Anti-SEMA4D (clone 5L9Q) SynExpress pB-mKa-I10-Sm γδ T cells

CAT#: ITS-1224-CR20
Clone: 5L9Q
Host: Mouse
Cell Source: γδ T cells
Species Reactivity: Human; Mouse
Connector Fragments: pBAD-mKate-IL-10-SmaI
Carrier Type: Lentivirus
Description
This product utilizes γδ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target SEMA4D (clone 5L9Q). We employs the Lentivirus (pBAD-mKate-IL-10-SmaI) vector components and the SynExpress system of the lncRNA Base Editing/Adaptive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
SEMA4D
Clone
5L9Q
Species Reactivity
Human; Mouse
Cell Source
γδ T cells
Sensor Gene
mKate
Promoter
pBAD
Effector Gene
IL-10
Insertion Sites
SmaI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
Lentivirus
Transformation Accuracy
0.89
Cell Culture
3D Culture
Target
SEMA4D
Alternative Names
SEMA4D; C9orf164; CD100; M-sema-G; SEMAJ; coll-4; semaphorin 4D; COLL4; A8; GR3; BB18
Gene ID
Q92854(Human)
UniProt ID
10507(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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