Over a decade of extensive experience in therapeutic protein drug discovery and development, Creative Biolabs has developed a comprehensive series of services including antibody discovery, antibody engineering, production, characterization, bioassay, in vivo testing, manufacture and development etc. We are dedicated to promoting your therapeutic antibody and protein candidates and accelerating the project to IND faster.
Leverage the expertise of our experienced scientists to expedite your therapeutic antibody and protein production.
Here is the general information about the advantages of four systems of heterologous protein expression for recombinant protein production. The more stars there are, the better the corresponding standpoint is.
(Kind reminder: Results may vary from one protein to another)
Expression system | Time | Cost | PTM | Low endotoxin levels | Simple process scale up |
Bacteria | ☆☆☆☆ | ☆☆☆☆ | ☆ | ☆ | ☆☆☆ |
Yeast | ☆ | ☆☆☆ | ☆☆ | ☆☆☆☆ | ☆☆ |
Insect | ☆ | ☆☆ | ☆☆☆ | ☆☆☆☆ | ☆ |
Mammalian cells | ☆☆☆ | ☆ | ☆☆☆☆ | ☆☆☆☆ | ☆☆ |
To ensure the best quality of our antibody and protein production service, including the highest purity of the product and the lowest risk of contamination, Creative Biolabs has developed several platforms supported by our recombinant protein production scientists. In addition, we also have quality control lab, molecular biology lab, etc. Our experienced experts will ensure to deliver protein products that fit our clients’ initial specifications.
We offer small to large-scale protein expression and purification services through 5 platforms as shown in above table at a competitive price. In the meanwhile, we provide advanced and custom service portfolio including screening in different expression systems in parallel or in different expression conditions in a given system. Our comprehensive service includes all phases from gene synthesis, vector construction to small scale protein production in flasks and large-scale protein production in bioreactors and fermenters.
We are committed to overcoming all potential obstacles related to solubility, refolding, purification, formulation, functionality and productivity, even for challenging proteins. With vast experience in the recombinant protein expression, such as enzymes, cytokines, or membrane proteins, etc. and antibodies including monoclonal antibody, bispecific antibody, anti-idiotype antibody, antibody-drug conjugates, etc., Creative Biolabs has developed complete production platforms to tackle any challenge in combination with discovery, engineering, bioassay and assay development, etc. For detailed information, please visit the following modules. If you are interested in any other specific requirements, please feel free to contact us to tailor a specific service for you.
We offer a transient expression in quick turnaround time with PTM available and low endotoxin levels...
We offer CHO transient protein production and stable large-scale protein production as one of the most popular mammalian systems...
We offer the most commonly used expression system with highlights including highly efficient reproduction, ease of culture, and well-studied genetics...
We offer flexible, effective and controllable solution for protein expression via our yeast protein production platform with features: easy genetic manipulation, high expression yields etc.
We have developed a variety of bacmids, enhanced insect cell lines, comprehensive technologies to assist protein expression with correct protein folding and post translational modifications...
We offer customized protein production services to best fit your specific requirements and maximize the success of your therapeutic antibody or protein product discovery and development...
As a leading protein production solution provider, Creative Biolabs is committed to guiding our clients from gene to protein to ensure the optimal strategy to fit the target protein features within budget and timeline. If you have antibody or protein production requirements, please contact us for more information and a detailed quote.
For lab research only, cannot be used for any clinical use.