ATM-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR63
Cell Type: DCs
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: PSPH
RNA types: rRNA
Modification: m7G
RNA editing: A to I
Short Description
This product is a ATM-targeted RNA modification and metabolomics analysis tool based on the m7G (METTL14-YTHDF2-ALKBH5-PSPH-Cy5.5) modification and Mevalonate pathway-mediated (α-synuclein-SAM-α-KG) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
PSPH
RNA types
rRNA
Modification
m7G
Label
Cy5.5
RNA editing
A to I
Cell Type
DCs
Oligonucleotide
PS, 2'-OMe, 2'-F, GalNAc
RNA Construction
rRNA-m7G-METTL14-YTHDF2-ALKBH5-PSPH-Cy5.5
Substrates
SAM
Cofactors
α-KG
Pathway
Mevalonate pathway
Epigenetic regulator
SMARCA4 deficiency
Metabolic alteration
Upregulating oxidative phosphorylation
Targeting diseases
Ovarian Cancers
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
Mevalonate pathway-α-synuclein-SAM-α-KG
Target
ATM
Alternative Names
ATM; ataxia telangiectasia mutated
Gene ID
472 (Human)
UniProt ID
Q13315 (Human)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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