ATP-targeted RNA Modification and Metabolomics Analysis Tool
CAT#: ITS-0524-CR82
Cell Type: CD4⁺ T Cells
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: PSAT1
RNA types: mRNAs
Modification: m5C
RNA editing: A to I
Short Description
This product is a ATP-targeted RNA modification and metabolomics analysis tool based on the m5C (METTL14-YTHDF2-ALKBH5-PSAT1-spacer C9) modification and Mevalonate pathway-mediated (NUDT21-SAM-NAD+) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
PSAT1
RNA types
mRNAs
Modification
m5C
Label
spacer C9
RNA editing
A to I
Cell Type
CD4⁺ T Cells
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-m5C-METTL14-YTHDF2-ALKBH5-PSAT1-spacer C9
Substrates
SAM
Cofactors
NAD+
Pathway
Mevalonate pathway
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Gastric Cancers
RNA-binding proteins
NUDT21
Metabolic Reprogramming
Mevalonate pathway-NUDT21-SAM-NAD+
Target
ATP
Alternative Names
Adenosine triphosphate (ATP
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.