BRD4/AMPK-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR14
Cell Type: M2 macrophages
RNA writers: TRMT6/61A
RNA readers: YTHDF1/2/3
RNA erasers: ALKBH7
Enzymes: KMTs
RNA types: mRNAs
Modification: ac4C
RNA editing: A to I
Short Description
This product is a BRD4/AMPK-targeted RNA modification and metabolomics analysis tool based on the ac4C (TRMT6/61A-YTHDF1/2/3-ALKBH7-KMTs-Thiol) modification and Mevalonate pathway-mediated (α-synuclein-SAM-NAD+) metabolic analysis system.
RNA writers
TRMT6/61A
RNA readers
YTHDF1/2/3
RNA erasers
ALKBH7
Enzymes
KMTs
RNA types
mRNAs
Modification
ac4C
Label
Thiol
RNA editing
A to I
Cell Type
M2 macrophages
Oligonucleotide
Undisclosed, GalNac
RNA Construction
mRNAs-ac4C-TRMT6/61A-YTHDF1/2/3-ALKBH7-KMTs-Thiol
Substrates
SAM
Cofactors
NAD+
Pathway
Mevalonate pathway
Epigenetic regulator
KDM4C overexpression
Metabolic alteration
Upregulating amino acids metabolism
Targeting diseases
Renal and Bladder Cancers
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
Mevalonate pathway-α-synuclein-SAM-NAD+
Target
BRD4/AMPK
Alternative Names
BRD4/AMPK
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
Online Inquiry