BRD4-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR20
Cell Type: M1 macrophages
RNA writers: METTL16
RNA readers: YTHDF3
RNA erasers: FTO
Enzymes: HATs
RNA types: rRNA
Modification: m1A
RNA editing: T to C
Short Description
This product is a BRD4-targeted RNA modification and metabolomics analysis tool based on the m1A (METTL16-YTHDF3-FTO-HATs-phos) modification and Mevalonate pathway-mediated (RBM9-SAM-NAD+) metabolic analysis system.
RNA writers
METTL16
RNA readers
YTHDF3
RNA erasers
FTO
Enzymes
HATs
RNA types
rRNA
Modification
m1A
Label
phos
RNA editing
T to C
Cell Type
M1 macrophages
Oligonucleotide
2'-MOE, GalNAc
RNA Construction
rRNA-m1A-METTL16-YTHDF3-FTO-HATs-phos
Substrates
SAM
Cofactors
NAD+
Pathway
Mevalonate pathway
Epigenetic regulator
SMARCA4 overexpression
Metabolic alteration
Upregulating fatty acids synthesis
Targeting diseases
Hepatocellular Carcinoma
RNA-binding proteins
RBM9
Metabolic Reprogramming
Mevalonate pathway-RBM9-SAM-NAD+
Target
BRD4
Alternative Names
BRD4; CAP; HUNK1; HUNKI; MCAP; bromodomain containing 4
Gene ID
23476(Human)
UniProt ID
O60885(Human)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
Online Inquiry