C1498 In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress)

This assay is to provide C1498-based In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.

C1498

Mouse

C1498 is a murine myeloid leukemia cell line isolated from a C57BL/6J mouse. It most closely resembles acute myeloid leukemia (AML), and is highly lethal when implanted into syngeneic mice.

Acute Myeloid Leukemia; AML

Oncology

In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress)

C1498-cell based In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress)

It's a commonly used simple antioxidant assay. The ability of antioxidants to reduce ABTS free radical (ABTS.) to ABTS is measured in the ABTS assay.

Oxidative Stress Assays

Disturbance between the production of reactive oxygen species (ROS), free radicals and antioxidant mechanisms is defined as the oxidative stress, or more precisely, it is an imbalance between the oxidant and antioxidant state in cells. This imbalance can cause harmful effects to cells and biomolecules, which ultimately causes adverse effects in the whole organism. Oxidative imbalance can target important proteinsand lipids in cells, which can increase the risk of developing a cancer. On the other hand, increased ROS production in cancer cells by certain cancer drugs can also arrest cancer cell cycle and cause senescence and apoptosis through oxidative stress.

Antioxidant Assay