C1498 In Vitro TOTO Assay (Cell Viability)

CAT#: ITS-1122-YF4640
Target Cell Organism: Mouse
Target Cell Name: C1498
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide C1498-based In Vitro TOTO Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
C1498
Target Cell Organism
Mouse
Target Cell Background
C1498 is a murine myeloid leukemia cell line isolated from a C57BL/6J mouse. It most closely resembles acute myeloid leukemia (AML), and is highly lethal when implanted into syngeneic mice.
Related Diseases
Acute Myeloid Leukemia; AML
Research Area
Oncology
Assay Name
In Vitro TOTO Assay (Cell Viability)
Short Description
C1498-cell based In Vitro TOTO Assay (Cell Viability)
Assay Description
The dyes in SYTOX family (blue, green, orange and red), TOTO and TO-PRO are other fluorescence dyes, which can penetrate only into dead cells to determine the cell viability.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Dye Exclusion Assays
For Research Use Only | Not For Clinical Use
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