This assay is to provide C1498-based In Vivo Tumorigenesis Assay to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
C1498
Target Cell Organism
Mouse
Target Cell Background
C1498 is a murine myeloid leukemia cell line isolated from a C57BL/6J mouse. It most closely resembles acute myeloid leukemia (AML), and is highly lethal when implanted into syngeneic mice.
Related Diseases
Acute Myeloid Leukemia; AML
Research Area
Oncology
Assay Name
In Vivo Tumorigenesis Assay
Short Description
C1498-cell based In Vivo Tumorigenesis Assay
Assay Description
Tumorigenicity is defined the property of a cell to form tumors when inoculated into an immunosuppressed animal model. Generally, test cells and tumor cells as positive control are administered subcutaneously into immunosuppressed nude mice. The number of animals developing tumors are compared with a positive control reference cell line.