Caco-2 In Vitro Micro-carrier Beads Assay (Angiogenesis)
CAT#: ITS-1022-YF5515
Target Cell Organism: Human
Target Cell Alternative Name: Caco2
Target Cell Name: Caco-2
Assay Type: Angiogenesis Monitoring Assays
Assay Overview
This assay is to provide Caco-2-based In Vitro Micro-carrier Beads Assay (Angiogenesis) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
Caco-2
Target Cell Organism
Human
Target Cell Background
Caco-2 [Caco2] are epithelial cells isolated from colon tissue derived from a 72-year-old, White, male with colorectal adenocarcinoma. This cell line is a suitable transfection host and has applications in cancer and toxicology research.
Target Cell Alternative Name
Caco2
Related Diseases
Colorectal Adenocarcinoma; Colon Cancer
Research Area
Oncology
Assay Name
In Vitro Micro-carrier Beads Assay (Angiogenesis)
Short Description
Caco-2-cell based In Vitro Micro-carrier Beads Assay (Angiogenesis)
Assay Description
Migration of cells from cell-coated micro-carrier beads to the surface of cell culture wells or dishes is measured in this assay. Cells are grown on the surface of carrieer beads and beads are then placed in a plate well or dish over particular incubation periods.
Assay Type
Angiogenesis Monitoring Assays
Assay Type Details
Local and regional metastasis is a life-threatening condition in cancer, which is hard to control with the available cancer treatment options. In metastasis, cancer cells move away from primary tumors and travel through the blood and lymphatic system and form new tumors on other parts. A vascular network growth is important for cancer metastasis. Angiogenesis is a process that is known as the formation of new blood vessels with the help of existing blood vessels and angiogenesis has been reported to play a major role in cancer growth and metastasis. Tumors can send chemical signals to nearby normal tissues to stimulate angiogenesis. New blood vessels can feed growing tumors with nutrients and oxygen, allowing cancer cells to spread (metastasis).