Creative Biolabs offers a comprehensive Cancer Metabolomics Analysis Service, utilizing cutting-edge technologies and expertise in the field of oncoimmunology. Our service provides a deep understanding of the metabolic alterations that occur in cancer cells, enabling researchers and clinicians to gain valuable insights into cancer biology and develop novel therapeutic strategies.
We use specialized techniques, including liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-mass spectrometry (GC-MS), enable accurate and sensitive detection of these metabolites in a variety of sample types, including tissues, biofluids, and cell cultures.
Targeted Metabolomics
Creative Biolabs offers targeted metabolomics services that focus on the quantification and analysis of a predefined set of metabolites. This approach allows for the precise measurement of specific metabolites known to be involved in cancer metabolism.
Untargeted Metabolomics
Creative Biolabs provides untargeted metabolomics services, which offer a comprehensive analysis of the complete metabolome in a given sample. Untargeted metabolomics allows for the unbiased identification and profiling of a broad range of metabolites, including known and unknown compounds.
Lipidomics
Creative Biolabs offers lipidomics services focusing on the comprehensive analysis of lipid species and their alterations in cancer. We can accurately quantify and characterize a wide range of lipid classes, including phospholipids, glycerolipids, and sphingolipids.
Creative Biolabs follows a rigorous and standardized process to ensure high-quality results in our Cancer Metabolomics Analysis Service. The process includes several key steps:
Sample Collection and Preparation
We work closely with our clients to determine the most suitable sample types for their specific research objectives. We provide detailed guidelines for sample collection, handling, and storage to ensure sample integrity. Our experts are available to offer support and guidance throughout this process.
Metabolite Extraction
We employ optimized protocols for efficient extraction of metabolites from the collected samples. Our methods ensure high extraction yields, minimal metabolite degradation, and reproducible results.
Metabolite Analysis
The extracted metabolites are subjected to advanced analytical techniques, such as LC-MS, GC-MS, and lipidomics platforms, depending on the specific service requested. These techniques allow for the separation, identification, and quantification of metabolites present in the samples.
Data Analysis and Report
Our bioinformatics experts employ sophisticated data analysis tools and algorithms to process the generated metabolomics data. We perform statistical analysis, pathway analysis, and integration with other omics data, such as genomics and proteomics, to unravel the complex metabolic alterations associated with cancer.
At Creative Biolabs, we understand that each cancer research project has unique requirements. To address this, we offer custom metabolite assay development services, allowing researchers to target specific metabolites of interest. Our experienced scientists collaborate closely with clients to design and optimize assays tailored to their specific needs. Through our custom metabolite assays, researchers can selectively measure and analyze the metabolites that are most relevant to their studies, enabling a more focused investigation of cancer metabolism.
Creative Biolabs has developed a series of Metabolomics Panels for Cancer. These panels comprise predefined sets of metabolites specifically selected for their relevance to cancer metabolism. By using these panels, researchers can perform targeted metabolomics analysis on a comprehensive range of metabolites associated with key metabolic pathways and cancer-specific alterations.
Amino Acids Targeted Metabolites
| Alanine | Methionine | Glutamine | Tyrosine |
| Arginine | Phenylalanine | Glycine | Valine |
| Asparagine | Proline | Histidine | Trans-4-hydroxyproline |
| Aspartic Acid | Serine | Isoleucine | Ornithine |
| Glutamic Acid | Threonine | Leucine | Citruline |
| Tryptophan | Lysine |
Bile Acids Targeted Metabolites
| Cholic Acid | Glycodeoxycholic Acid | Taurodeoxycholic Acid | Ursodeoxycholic Acid |
| Chenodeoxycholic Acid | Glycoursodeoxycholic Acid | Taurolithocholic Acid | Glycocholic Acid |
| Deoxycholic Acid | Taurocholic Acid | Tauroursodeoxycholic Acid | Glycochenodeoxycholic Acid |
| Lithocholic Acid | Taurochenodeoxycholic Acid | Glycolithocholic Acid |
Central Carbons Targeted Metabolites
| Lactic Acid | Succinic Acid |
| Pyruvic Acid | Malic Acid |
| Citric Acid | Fumaric Acid |
| 2-Ketoglutaric Acid |
Free Fatty Acids Targeted Metabolites
| Palmitic Acid | Oleic Acid |
| Palmitoleic Acid | Linoleic Acid |
| Margaric Acid | Linolenic Acid |
| Stearic Acid |
Creative Biolabs' Cancer Metabolomics Analysis Service offers a comprehensive suite of services for studying the metabolic alterations in cancer. Through our targeted and untargeted metabolomics approaches, combined with lipidomics capabilities, we provide valuable insights into cancer metabolism, potential biomarkers, and therapeutic targets. Please feel free to contact us for more about our Cancer Microbiome Profiling services.
For Research Use Only | Not For Clinical Use
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