Catechol Oxidase-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR175
Cell Type: M2 macrophages
RNA writers: PCIF1
RNA readers: /
RNA erasers: FTO
Enzymes: D2HGDH
RNA types: mRNAs
Modification: ac4C
RNA editing: G to A
Short Description
This product is a Catechol oxidase-targeted RNA modification and metabolomics analysis tool based on the ac4C (PCIF1-FTO-D2HGDH-spacer C9) modification and Gluconeogenesis-mediated (MBNL-Succinyl-CoA-α-KG) metabolic analysis system.
RNA writers
PCIF1
RNA readers
/
RNA erasers
FTO
Enzymes
D2HGDH
RNA types
mRNAs
Modification
ac4C
Label
spacer C9
RNA editing
G to A
Cell Type
M2 macrophages
Oligonucleotide
PO, 2'-OMe, ENA
RNA Construction
mRNAs-ac4C-PCIF1-FTO-D2HGDH-spacer C9
Substrates
Succinyl-CoA
Cofactors
α-KG
Pathway
Gluconeogenesis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Colorectal Cancer
RNA-binding proteins
MBNL
Metabolic Reprogramming
Gluconeogenesis-MBNL-Succinyl-CoA-α-KG
Target
Catechol oxidase
Alternative Names
Catechol oxidase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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