Development Stage: Research-Grade Cellular Function Assay Development
Short Description
Improved method for urea quantification with enhanced stability.
Brand
CelluTest
Development Stage
Research-Grade Cellular Function Assay Development
Description
The CelluTest™ Urea Assay Kit III provides an improved formulation for determining blood urea nitrogen (BUN), minimizing ammonia interference in complex biological samples. This assay is a standard component of nephrotoxicity screening panels, helping to identify drug-induced renal impairment early in development. It ensures accurate assessment of kidney function in toxicology studies involving diverse drug matrices.
Features
Improved formulation reduces ammonia interference; Ideal for nephrotoxicity screening in complex drug matrices.
Process Relevance
Renal Function Testing (Tox)
Application Stage
Pre-clinical Safety
Applications
Nephrotoxicity screening and renal function testing in biological fluids.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 340 nm
Sample Type
Urea in biological samples (e.g. plasma, serum, urine, bronchoalveolar lavage (BAL)) and food/beverage samples (e.g. milk)
Research Areas
Nephrology; Toxicology
Size
100 tests
Data Output Type
Quantitative (Concentration)
Assay Time
Results in 30 min
LOD
50 µM
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Urea is the primary vehicle for nitrogen excretion formed in the liver via the urea cycle. Blood Urea Nitrogen (BUN) is a standard clinical marker for kidney function and protein metabolism balance.