LAL test relys on factor C coagulation cascade found in horseshoe crabs' blood. The combination of endotoxin and zymogen factor C initiate the protease cascade. Next, the activated factor C goes onto activate factor B, which converts the proclotting enzyme to the clotting enzyme. Lastly, two peptide bonds in coagulogen are catalytically cleaved to form coagulin gel.
Qualified With
Quality Certificate
Target
Endotoxin
Detection Method
Chromogenic
Method Type
Lyophilized amebocyte lysate (LAL)
Size
1 Kit (32 rxns)
Sensitivity
0.01 to 1 EU/mL
Assay Procedure
See manual for details.
Storage
dry at room temperature for up to one month; 2-8°C for up to 24 months; Do not freeze
Note
Our ELISA kit assays are versatile research tools that may be updated and enhanced over time. Please feel free to contact us for more product information to review, validate and evaluate information before purchasing a kit.