Assay Name
In Vitro Activator/Inhibitor Screening Assay
Short Description
Screen for activators or inhibitors of CTLA4 signaling in a cellular context.
Assay Description
Creative Biolabs has developed several I-O function assay based on our stable cell Lines expressed the most popular immune checkpoints. CTLA4 (Human) Activator/Inhibitor Screening Assay, Jurkat (CTLA4 & IL-2)-based is applied to screen for activators or inhibitors of CTLA4 signaling in a cellular context. The assay will be customized according to the client's specific requirements. Please contact our scientists to discuss more details.
Assay Alternative Names
In Vitro Activator/Inhibitor Screening Assay; Activator/Inhibitor Screening Assay
Assay Reporter
IL-2 Reporter
Assay Type
Activator/Inhibitor Screening Assay
Assay MOA
Creative Biolabs has developed several immune checkpoint stable cell Lines expressing the most popular immune checkpoints to accelerate clients' immunotherapy discovery and clinical translation. Recombinant Jurkat T cell expressing firefly luciferase gene under the control of IL-2 promoter with constitutive expression of human CTLA4 (Cytotoxic T-Lymphocyte Associated Protein, CD152; GenBank Accession #NM_005214). Which can be used in binding assays and functional assay.
Datasheet