Description
Researchers at the Creative Biolabs have developed Cynomolgus Monkey CD14+ Cells, purified that allows for study in numerous research areas, such as immunology, oncology. The cells can be used for a wide variety of safety assessment and functional assays.
Species character
The cynomolgus macaque is the most commonly utilized non-human primate in biomedical research. According to some researchers, these monkeys are ideal models due to the 90-93% genetic similarity to and recent evolutionary divergence from humans. They are employed in numerous research areas, such as immunology, neuroscience, oncology, diabetes, and pharmacology due to their genetics and physiology.
Background
CD14+ cells make up approximately a third of cells in the blood of a typical adult monkey. Monocytes and neutrophils typically make up the cells that express CD14+ cells. When activated, monocytes can phagocytose foreign cells and perform antibody-dependent cellular phagocytosis (ADCP). They can also produce and secrete inflammatory cytokines. Developmentally, monocytes can mature into macrophages and dendritic cells depending on the soluble factors they are exposed to in order to become more specialized immune subsets.
Species
Cynomolgus Monkey
Cell type
CD14+ Cells

For Research Use Only | Not For Clinical Use

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