CYP2D6-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR189
Cell Type: CD8 T Cells
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: ACL
RNA types: mRNAs
Modification: m7G
RNA editing: C to U
Short Description
This product is a CYP2D6-targeted RNA modification and metabolomics analysis tool based on the m7G (METTL14-YTHDF2-ALKBH5-ACL-MGB) modification and Fatty acid metabolism-mediated (HTT-Acetyl-CoA-α-KG) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
ACL
RNA types
mRNAs
Modification
m7G
Label
MGB
RNA editing
C to U
Cell Type
CD8 T Cells
Oligonucleotide
2'-OMe (cationic lipoplex)
RNA Construction
mRNAs-m7G-METTL14-YTHDF2-ALKBH5-ACL-MGB
Substrates
Acetyl-CoA
Cofactors
α-KG
Pathway
Fatty acid metabolism
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
HTT
Metabolic Reprogramming
Fatty acid metabolism-HTT-Acetyl-CoA-α-KG
Target
CYP2D6
Alternative Names
CYP2D6; CPD6; CYP2D; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; CYP2DL1; CYPIID6; P450-DB1; P450C2D; P450DB1; cytochrome P450 family 2 subfamily D member 6; Cytochrome P450 2D6
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
Online Inquiry