DIO3-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR209
Cell Type: CD8 T Cells
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: ACL
RNA types: tRNA
Modification: ψ
RNA editing: C to U
Short Description
This product is a DIO3-targeted RNA modification and metabolomics analysis tool based on the ψ (METTL3-YTHDF1-FTO-ACL-spacer C9) modification and Glycogen synthesis-mediated (TDP-43-Acetyl-CoA-ATP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
ACL
RNA types
tRNA
Modification
ψ
Label
spacer C9
RNA editing
C to U
Cell Type
CD8 T Cells
Oligonucleotide
LNA
RNA Construction
tRNA-ψ-METTL3-YTHDF1-FTO-ACL-spacer C9
Substrates
Acetyl-CoA
Cofactors
ATP
Pathway
Glycogen synthesis
Epigenetic regulator
KMT2D inhibition
Metabolic alteration
Upregulating glycolysis and lipids metabolism
Targeting diseases
Renal and Bladder Cancers
RNA-binding proteins
TDP-43
Metabolic Reprogramming
Glycogen synthesis-TDP-43-Acetyl-CoA-ATP
Target
DIO3
Alternative Names
DIO3; 5DIII; D3; DIOIII; TXDI3; deiodinase; iodothyronine; type III; iodothyronine deiodinase 3; Dio3 Gene
Gene ID
1735(Human); 107585(Mouse); 29475(Rat)
UniProt ID
P55073(Human); Q91ZI8(Mouse); P49897(Rat)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
Online Inquiry