DND-41 In Vitro 7-Aminoactinomycin D Assay (Cell Viability)

CAT#: ITS-1122-YF5163
Target Cell Organism: Human
Target Cell Name: DND-41
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide DND-41-based In Vitro 7-Aminoactinomycin D Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
DND-41
Target Cell Organism
Human
Target Cell Background
DND-41 was established from the peripheral blood of 13-year-old boy with T-acute lymphoblastic leukemia (T-ALL; type III cortical) in 1977; described to carry CDKN2B (p15INK4B) and CDKN2A (p16INK4A) deletions and TP53 (p53)mutation.
Related Diseases
Acute Lymphoblastic Leukemia; ALL
Research Area
Oncology
Assay Name
In Vitro 7-Aminoactinomycin D Assay (Cell Viability)
Short Description
DND-41-cell based In Vitro 7-Aminoactinomycin D Assay (Cell Viability)
Assay Description
7-Aminoactinomycin D is a fluo rescent dye that can also be used to detect viable/non-viable cells (excluded by viable cells) by fluorescence microscopy and FCM.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Dye Exclusion Assays
For Research Use Only | Not For Clinical Use
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