DND-41 In Vitro Protein Expression Analysis Assay (Western Blot)

This assay is to provide DND-41-based In Vitro Protein Expression Analysis Assay (Western Blot) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.

DND-41

Human

DND-41 was established from the peripheral blood of 13-year-old boy with T-acute lymphoblastic leukemia (T-ALL; type III cortical) in 1977; described to carry CDKN2B (p15INK4B) and CDKN2A (p16INK4A) deletions and TP53 (p53)mutation.

Acute Lymphoblastic Leukemia; ALL

Oncology

In Vitro Protein Expression Analysis Assay (Western Blot)

DND-41-cell based In Vitro Protein Expression Analysis Assay (Western Blot)

For protein expression, western blotting and immunoassays have provided high-quality quantitative results. 2D gel electrophoresis

Gene and Protein Expression Assays

Following transcription, primary transcript RNA is converted into mature RNA by post-transcriptional modifications. Post-transcriptional modification includes three major steps namely the addition of a 5'cap, addition of a 3'polyadenylation tail and RNA splicing. Stability of RNA has been considered as very important for gene expression and proteins at the post-transcriptional level.