DNMT-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR1
Cell Type: CD8 T Cells
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: PHGDH
RNA types: mRNAs
Modification: m6A
RNA editing: C to U
Short Description
This product is a DNMT-targeted RNA modification and metabolomics analysis tool based on the m6A (METTL3-YTHDF1-FTO-PHGDH-Cholesterol) modification and Glycolysis-mediated (CPEB4-Acetyl-CoA-α-KG) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
PHGDH
RNA types
mRNAs
Modification
m6A
Label
Cholesterol
RNA editing
C to U
Cell Type
CD8 T Cells
Oligonucleotide
2'-MOE
RNA Construction
mRNAs-m6A-METTL3-YTHDF1-FTO-PHGDH-Cholesterol
Substrates
Acetyl-CoA
Cofactors
α-KG
Pathway
Glycolysis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
CPEB4
Metabolic Reprogramming
Glycolysis-CPEB4-Acetyl-CoA-α-KG
Target
DNMT
Alternative Names
DNA methyltransferase; DNA MTase; DNMT
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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