LAL test relys on factor C coagulation cascade found in horseshoe crabs' blood. The combination of endotoxin and zymogen factor C initiate the protease cascade. Next, the activated factor C goes onto activate factor B, which converts the proclotting enzyme to the clotting enzyme. Lastly, two peptide bonds in coagulogen are catalytically cleaved to form coagulin gel.
Qualified With
Quality Certificate
Target
Endotoxin
Detection Method
Chromogenic
Method Type
Lyophilized amebocyte lysate (LAL)
Size
64 tests
Sensitivity
0.1 to 1 EU/mL
Assay Time
16 minutes
Assay Procedure
See manual for details.
Note
Our ELISA kit assays are versatile research tools that may be updated and enhanced over time. Please feel free to contact us for more product information to review, validate and evaluate information before purchasing a kit.