Fld-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR149
Cell Type: M1 macrophages
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: ACL
RNA types: tRNA
Modification: ac4C
RNA editing: A to I
Short Description
This product is a Fld-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL3-YTHDF1-FTO-ACL-Thiol) modification and Mevalonate pathway-mediated (TDP-43-Acetyl-CoA-ATP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
ACL
RNA types
tRNA
Modification
ac4C
Label
Thiol
RNA editing
A to I
Cell Type
M1 macrophages
Oligonucleotide
PS, 2'-OMe, 2'-F, GalNAc
RNA Construction
tRNA-ac4C-METTL3-YTHDF1-FTO-ACL-Thiol
Substrates
Acetyl-CoA
Cofactors
ATP
Pathway
Mevalonate pathway
Epigenetic regulator
KMT2D inhibition
Metabolic alteration
Upregulating glycolysis and lipids metabolism
Targeting diseases
Colorectal Cancer
RNA-binding proteins
TDP-43
Metabolic Reprogramming
Mevalonate pathway-TDP-43-Acetyl-CoA-ATP
Target
Fld
Alternative Names
Flavodoxins (Fld
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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