FOXO6-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR338
Cell Type: M2 macrophages
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: NMNAT1
RNA types: rRNA
Modification: m1A
RNA editing: A to I
Short Description
This product is a FOXO6-targeted RNA modification and metabolomics analysis tool based on the m1A (METTL14-YTHDF2-ALKBH5-NMNAT1-spacer C18) modification and Fatty acid synthesis-mediated (α-synuclein-SAM-NAD+) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
NMNAT1
RNA types
rRNA
Modification
m1A
Label
spacer C18
RNA editing
A to I
Cell Type
M2 macrophages
Oligonucleotide
2'-OMe (cationic lipoplex)
RNA Construction
rRNA-m1A-METTL14-YTHDF2-ALKBH5-NMNAT1-spacer C18
Substrates
SAM
Cofactors
NAD+
Pathway
Fatty acid synthesis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
Fatty acid synthesis-α-synuclein-SAM-NAD+
Target
FOXO6
Alternative Names
FOXO6; forkhead box O6
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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