GCK-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR143
Cell Type: M1 macrophages
RNA writers: METTL16
RNA readers: YTHDF3
RNA erasers: FTO
Enzymes: PSPH
RNA types: mRNAs
Modification: ψ
RNA editing: G to A
Short Description
This product is a GCK-targeted RNA modification and metabolomics analysis tool based on the ψ (METTL16-YTHDF3-FTO-PSPH-BHQ3) modification and PPP-mediated (hnRNPs-Succinyl-CoA-α-KG) metabolic analysis system.
RNA writers
METTL16
RNA readers
YTHDF3
RNA erasers
FTO
Enzymes
PSPH
RNA types
mRNAs
Modification
ψ
Label
BHQ3
RNA editing
G to A
Cell Type
M1 macrophages
Oligonucleotide
2'-OMe
RNA Construction
mRNAs-ψ-METTL16-YTHDF3-FTO-PSPH-BHQ3
Substrates
Succinyl-CoA
Cofactors
α-KG
Pathway
PPP
Epigenetic regulator
KMT2D deficiency
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Endometrial Cancers
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
PPP-hnRNPs-Succinyl-CoA-α-KG
Target
GCK
Alternative Names
GCK; FGQTL3; GK; GLK; HHF3; HK4; HKIV; HXKP; LGLK; MODY2; glucokinase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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