GCS-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR367
Cell Type: M2 macrophages
RNA writers: METTL16
RNA readers: YTHDF3
RNA erasers: FTO
Enzymes: ACSS2
RNA types: mRNAs
Modification: m6A
RNA editing: G to A
Short Description
This product is a GCS-targeted RNA modification and metabolomics analysis tool based on the m6A (METTL16-YTHDF3-FTO-ACSS2-BHQ2) modification and Fatty acid synthesis-mediated (NUDT21-Succinyl-CoA-ADP) metabolic analysis system.
RNA writers
METTL16
RNA readers
YTHDF3
RNA erasers
FTO
Enzymes
ACSS2
RNA types
mRNAs
Modification
m6A
Label
BHQ2
RNA editing
G to A
Cell Type
M2 macrophages
Oligonucleotide
2'-OMe (cationic lipoplex)
RNA Construction
mRNAs-m6A-METTL16-YTHDF3-FTO-ACSS2-BHQ2
Substrates
Succinyl-CoA
Cofactors
ADP
Pathway
Fatty acid synthesis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Glioma
RNA-binding proteins
NUDT21
Metabolic Reprogramming
Fatty acid synthesis-NUDT21-Succinyl-CoA-ADP
Target
GCS
Alternative Names
Glycine cleavage system; GCS
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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