GIST-T1 In Vitro LDH Assay (Cell Viability)

CAT#: ITS-1122-YF2845
Target Cell Organism: Human
Target Cell Name: GIST-T1
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide GIST-T1-based In Vitro LDH Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
GIST-T1
Target Cell Organism
Human
Target Cell Background
A new human cell line, GIST-T1, was established from a metastatic plural tumor from a gastrointestinal stromal tumor (GIST) of the stomach in a Japanese woman, and was characterized by immunohistochemistry, conventional banding methods, comparative genomic hybridization (CGH), and fluorescence in situ hybridization (FISH).
Related Diseases
Gastrointestinal Stromal Tumor; GIST
Research Area
Oncology
Assay Name
In Vitro LDH Assay (Cell Viability)
Short Description
GIST-T1-cell based In Vitro LDH Assay (Cell Viability)
Assay Description
Lactate dehydrogenase leakage assay (LDH assay) can also be used to determine viability of cancer cells. Upon treatment with a testing drug, if the drug can rupture the cell membrane, cells release LDH to the culture medium and released LDH can be quantified.
Assay Alternative Names
Lactate Dehydrogenase Leakage Assay
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Cell-based Viability Assays Based on Cellular Enzymes and Proteins
For Research Use Only | Not For Clinical Use
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