GL261 In Vitro Evans Blue Assay (Cell Viability)

CAT#: ITS-1022-YF233
Target Cell Organism: Mouse
Target Cell Alternative Name: Glioma 261
Target Cell Name: GL261
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide GL261-based In Vitro Evans Blue Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
GL261
Target Cell Organism
Mouse
Target Cell Background
Glioma 261 (GL261) is a frequently used murine glioma model. It was induced via intracranial injection of methylcholanthrene followed by serial intracranial and subcutaneous transplantations of tumor fragments into syngeneic C57BL/6 mice. By the mid-1990s, multiple groups had established a permanent cell line from the tumor.
Target Cell Alternative Name
Glioma 261
Related Diseases
Glioma
Research Area
Oncology
Assay Name
In Vitro Evans Blue Assay (Cell Viability)
Short Description
GL261-cell based In Vitro Evans Blue Assay (Cell Viability)
Assay Description
The dye Evans blue has also been used in cell viability assays based on its ability to cross non-viable cell membranes.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Dye Exclusion Assays
For Research Use Only | Not For Clinical Use
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