GLS-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR6
Cell Type: M2 macrophages
RNA writers: METTL14
RNA readers: HNRNPs
RNA erasers: ALKBH5
Enzymes: KMTs
RNA types: rRNA
Modification: ψ
RNA editing: A to I
Short Description
This product is a GLS-targeted RNA modification and metabolomics analysis tool based on the ψ (METTL14-HNRNPs-ALKBH5-KMTs-spacer C18) modification and Glycolysis-mediated (hnRNPs-SAM-NAD+) metabolic analysis system.
RNA writers
METTL14
RNA readers
HNRNPs
RNA erasers
ALKBH5
Enzymes
KMTs
RNA types
rRNA
Modification
ψ
Label
spacer C18
RNA editing
A to I
Cell Type
M2 macrophages
Oligonucleotide
cET, 2'-MOE
RNA Construction
rRNA-ψ-METTL14-HNRNPs-ALKBH5-KMTs-spacer C18
Substrates
SAM
Cofactors
NAD+
Pathway
Glycolysis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Glycolysis-hnRNPs-SAM-NAD+
Target
GLS
Alternative Names
Glutaminase; GLS
Gene ID
2744(Human)
UniProt ID
O94925(Human)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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