Glucagon-targeted RNA Modification and Metabolomics Analysis Tool
CAT#: ITS-0524-CR132
Cell Type: M1 macrophages
RNA writers: DNMT2
RNA readers: ALYREF
RNA erasers: ALKBH1
Enzymes: FDH
RNA types: mRNAs
Modification: m1A
RNA editing: T to C
Short Description
This product is a Glucagon-targeted RNA modification and metabolomics analysis tool based on the m1A (DNMT2-ALYREF-ALKBH1-FDH-TAMRA) modification and Mevalonate pathway-mediated (α-synuclein-SAM-ADP) metabolic analysis system.
RNA writers
DNMT2
RNA readers
ALYREF
RNA erasers
ALKBH1
Enzymes
FDH
RNA types
mRNAs
Modification
m1A
Label
TAMRA
RNA editing
T to C
Cell Type
M1 macrophages
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-m1A-DNMT2-ALYREF-ALKBH1-FDH-TAMRA
Substrates
SAM
Cofactors
ADP
Pathway
Mevalonate pathway
Epigenetic regulator
G9A overexpression
Metabolic alteration
Upregulating serine-glycine biosyntheticpathway
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
Mevalonate pathway-α-synuclein-SAM-ADP
Target
Glucagon
Alternative Names
Glucagon
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.