Glucocorticoids-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR337
Cell Type: M1 macrophages
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: SIRT1
RNA types: mRNAs
Modification: ac4C
RNA editing: C to U
Short Description
This product is a glucocorticoids-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL3-YTHDF1-FTO-SIRT1-phos) modification and Fatty acid synthesis-mediated (NUDT21-Acetyl-CoA-α-KG) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
SIRT1
RNA types
mRNAs
Modification
ac4C
Label
phos
RNA editing
C to U
Cell Type
M1 macrophages
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-ac4C-METTL3-YTHDF1-FTO-SIRT1-phos
Substrates
Acetyl-CoA
Cofactors
α-KG
Pathway
Fatty acid synthesis
Epigenetic regulator
SIRT6 deficiency
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Prostate Cancers
RNA-binding proteins
NUDT21
Metabolic Reprogramming
Fatty acid synthesis-NUDT21-Acetyl-CoA-α-KG
Target
glucocorticoids
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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