GOT1-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR54
Cell Type: M1 macrophages
RNA writers: WBSCR22
RNA readers: eIF4E; CBC
RNA erasers: /
Enzymes: ALKBH5
RNA types: rRNA
Modification: ac4C
RNA editing: A to I
Short Description
This product is a GOT1-targeted RNA modification and metabolomics analysis tool based on the ac4C (WBSCR22-eIF4E; CBC-ALKBH5-MGB) modification and Mevalonate pathway-mediated (HTT-SAM-ATP) metabolic analysis system.
RNA writers
WBSCR22
RNA readers
eIF4E; CBC
RNA erasers
/
Enzymes
ALKBH5
RNA types
rRNA
Modification
ac4C
Label
MGB
RNA editing
A to I
Cell Type
M1 macrophages
Oligonucleotide
PS, 2'-OMe, 2'-F, GalNAc
RNA Construction
rRNA-ac4C-WBSCR22-eIF4E; CBC-ALKBH5-MGB
Substrates
SAM
Cofactors
ATP
Pathway
Mevalonate pathway
Epigenetic regulator
KDM4C overexpression
Metabolic alteration
Upregulating amino acids metabolism
Targeting diseases
Glioblastoma
RNA-binding proteins
HTT
Metabolic Reprogramming
Mevalonate pathway-HTT-SAM-ATP
Target
GOT1
Alternative Names
GOT1; ASTQTL1; GIG18; cAspAT; cCAT; AST1; glutamic-oxaloacetic transaminase 1
Gene ID
51026(Human)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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