GSK-3-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR134
Cell Type: CD4⁺ T Cells
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: HDACs
RNA types: tRNA
Modification: m6A
RNA editing: A to I
Short Description
This product is a GSK-3-targeted RNA modification and metabolomics analysis tool based on the m6A (METTL14-YTHDF2-ALKBH5-HDACs-Thiol) modification and Glycogen synthesis-mediated (TDP-43-SAM-NAD+) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
HDACs
RNA types
tRNA
Modification
m6A
Label
Thiol
RNA editing
A to I
Cell Type
CD4⁺ T Cells
Oligonucleotide
PS, 2'-OMe, 2'-F, GalNAc
RNA Construction
tRNA-m6A-METTL14-YTHDF2-ALKBH5-HDACs-Thiol
Substrates
SAM
Cofactors
NAD+
Pathway
Glycogen synthesis
Epigenetic regulator
SMARCA4 deficiency
Metabolic alteration
Upregulating oxidative phosphorylation
Targeting diseases
Gastric Cancers
RNA-binding proteins
TDP-43
Metabolic Reprogramming
Glycogen synthesis-TDP-43-SAM-NAD+
Target
GSK-3
Alternative Names
Glycogen synthase kinase 3; GSK-3
Gene ID
2932(Human); 56637(Mouse); 84027(Rat)
UniProt ID
P49841(Human); Q9WV60(Mouse); P18266(Rat)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
Online Inquiry