GTFs-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR127
Cell Type: M1 macrophages
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: ACSS2
RNA types: mRNAs
Modification: ψ
RNA editing: G to A
Short Description
This product is a GTFs-targeted RNA modification and metabolomics analysis tool based on the ψ (METTL3-YTHDF1-FTO-ACSS2-phos) modification and Mevalonate pathway-mediated (α-synuclein-SAM-ADP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
ACSS2
RNA types
mRNAs
Modification
ψ
Label
phos
RNA editing
G to A
Cell Type
M1 macrophages
Oligonucleotide
PS, 2'-OMe, 2'-F, GalNAc
RNA Construction
mRNAs-ψ-METTL3-YTHDF1-FTO-ACSS2-phos
Substrates
SAM
Cofactors
ADP
Pathway
Mevalonate pathway
Epigenetic regulator
PKCλ/ι deficiency
Metabolic alteration
Favor the development of NEPC characteristics
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
Mevalonate pathway-α-synuclein-SAM-ADP
Target
GTFs
Alternative Names
Glycosyltransferases; GTFs
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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