GULOP-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR159
Cell Type: M2 macrophages
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: NAMPT
RNA types: mRNAs
Modification: ac4C
RNA editing: A to I
Short Description
This product is a GULOP-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL14-YTHDF2-ALKBH5-NAMPT-MGB) modification and Fatty acid metabolism-mediated (HTT-Succinyl-CoA-α-KG) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
NAMPT
RNA types
mRNAs
Modification
ac4C
Label
MGB
RNA editing
A to I
Cell Type
M2 macrophages
Oligonucleotide
LNA
RNA Construction
mRNAs-ac4C-METTL14-YTHDF2-ALKBH5-NAMPT-MGB
Substrates
Succinyl-CoA
Cofactors
α-KG
Pathway
Fatty acid metabolism
Epigenetic regulator
SMARCA4 deficiency
Metabolic alteration
Upregulating oxidative phosphorylation
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
HTT
Metabolic Reprogramming
Fatty acid metabolism-HTT-Succinyl-CoA-α-KG
Target
GULOP
Alternative Names
GULOP; GULO; SCURVY; gulonolactone (L-) oxidase; pseudogene
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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